Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?

BACKGROUND: HIV infection and biomarkers of inflammation [measured by interleukin-6 (IL-6)], monocyte activation [soluble CD14 (sCD14)], and coagulation (D-dimer) are associated with morbidity and mortality. We hypothesized that these immunologic processes mediate (explain) some of the excess risk o...

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Veröffentlicht in:J Acquir Immune Defic Syndr
Hauptverfasser: So-Armah, Kaku A., Tate, Janet P., Chang, Chung-Chou H., Butt, Adeel A., Gerschenson, Mariana, Gibert, Cynthia L., Leaf, David, Rimland, David, Rodriguez-Barradas, Maria C., Budoff, Matthew J., Samet, Jeffrey H., Kuller, Lewis H., Deeks, Steven G., Crothers, Kristina, Tracy, Russell P., Crane, Heidi M., Sajadi, Mohammad M., Tindle, Hilary A., Justice, Amy C., Freiberg, Matthew S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Schlagworte:
Epidemiology and Prevention
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867134/
https://ncbi.nlm.nih.gov/pubmed/27824677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000954
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