Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?

BACKGROUND: HIV infection and biomarkers of inflammation [measured by interleukin-6 (IL-6)], monocyte activation [soluble CD14 (sCD14)], and coagulation (D-dimer) are associated with morbidity and mortality. We hypothesized that these immunologic processes mediate (explain) some of the excess risk o...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: So-Armah, Kaku A., Tate, Janet P., Chang, Chung-Chou H., Butt, Adeel A., Gerschenson, Mariana, Gibert, Cynthia L., Leaf, David, Rimland, David, Rodriguez-Barradas, Maria C., Budoff, Matthew J., Samet, Jeffrey H., Kuller, Lewis H., Deeks, Steven G., Crothers, Kristina, Tracy, Russell P., Crane, Heidi M., Sajadi, Mohammad M., Tindle, Hilary A., Justice, Amy C., Freiberg, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado em: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Assuntos:
Epidemiology and Prevention
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867134/
https://ncbi.nlm.nih.gov/pubmed/27824677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000954
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