CD57(+) CD4 T cells underlie belatacept-resistant allograft rejection

Belatacept is a B7-specific fusion protein used to prevent allograft rejection by blocking T cell costimulation. Generally efficacious, it fails to prevent acute rejection in a sizable minority of patients. In experimental models, memory T cells mediate costimulation blockade-resistant rejection (Co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Transplant
Prif Awduron: Espinosa, Jaclyn, Herr, Florence, Tharp, Gregory, Bosinger, Steven, Song, Mingqing, Farris, Alton Brad, George, Roshan, Cheeseman, Jennifer, Stempora, Linda, Townsend, Robert, Durrbach, Antoine, Kirk, Allan D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867077/
https://ncbi.nlm.nih.gov/pubmed/26603381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13613
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg