MRI texture features as biomarkers to predict MGMT methylation status in glioblastomas

PURPOSE: Imaging biomarker research focuses on discovering relationships between radiological features and histological findings. In glioblastoma patients, methylation of the O(6)-methylguanine methyltransferase (MGMT) gene promoter is positively correlated with an increased effectiveness of current...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Med Phys
Hauptverfasser: Korfiatis, Panagiotis, Kline, Timothy L., Coufalova, Lucie, Lachance, Daniel H., Parney, Ian F., Carter, Rickey E., Buckner, Jan C., Erickson, Bradley J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association of Physicists in Medicine 2016
Schlagworte:
QUANTITATIVE IMAGING AND IMAGE PROCESSING
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866963/
https://ncbi.nlm.nih.gov/pubmed/27277032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1118/1.4948668
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