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Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumor using whole genome sequencing
Wilms tumor (WT), a pediatric renal cancer, is the most common childhood kidney cancer. The etiology of WT is heterogeneous with multiple genes known to result in WT tumorigenesis. However, these genes are rarely associated with familial Wilms tumor (FWT). To identify mutations predisposing to FWT,...
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| Publicado no: | J Med Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4866907/ https://ncbi.nlm.nih.gov/pubmed/26566882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103311 |
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