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Enantioselective CuH-Catalyzed Reductive Coupling of Aryl Alkenes and Activated Carboxylic Acids

[Image: see text] A new method for the enantioselective reductive coupling of aryl alkenes with activated carboxylic acid derivatives via copper hydride catalysis is described. Dual catalytic cycles are proposed, with a relatively fast enantioselective hydroacylation cycle followed by a slower diast...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Bandar, Jeffrey S., Ascic, Erhad, Buchwald, Stephen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2016
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866599/
https://ncbi.nlm.nih.gov/pubmed/27121395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03086
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