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Maternal IgG and IgA antibodies dampen mucosal T helper cell responses in early life

To maintain a symbiotic relationship between the host and its resident intestinal microbiota, appropriate mucosal T cell responses to commensal antigens must be established. Mice acquire both IgG and IgA maternally; the former has primarily been implicated in passive immunity to pathogens while the...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Koch, Meghan A., Reiner, Gabrielle L., Lugo, Kyler A., Kreuk, Lieselotte S.M., Stanbery, Alison G., Ansaldo, Eduard, Seher, Thaddeus D., Ludington, William B., Barton, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866587/
https://ncbi.nlm.nih.gov/pubmed/27153495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.055
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