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Skeletal Muscle, but not Cardiovascular Function, Is Altered in a Mouse Model of Autosomal Recessive Hypophosphatemic Rickets

Autosomal recessive hypophosphatemic rickets (ARHR) is a heritable disorder characterized by hypophosphatemia, osteomalacia, and poor bone development. ARHR results from inactivating mutations in the DMP1 gene with the human phenotype being recapitulated in the Dmp1 null mouse model which displays e...

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Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Wacker, Michael J., Touchberry, Chad D., Silswal, Neerupma, Brotto, Leticia, Elmore, Chris J., Bonewald, Lynda F., Andresen, Jon, Brotto, Marco
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866514/
https://ncbi.nlm.nih.gov/pubmed/27242547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00173
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