Skeletal Muscle, but not Cardiovascular Function, Is Altered in a Mouse Model of Autosomal Recessive Hypophosphatemic Rickets

Autosomal recessive hypophosphatemic rickets (ARHR) is a heritable disorder characterized by hypophosphatemia, osteomalacia, and poor bone development. ARHR results from inactivating mutations in the DMP1 gene with the human phenotype being recapitulated in the Dmp1 null mouse model which displays e...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Wacker, Michael J., Touchberry, Chad D., Silswal, Neerupma, Brotto, Leticia, Elmore, Chris J., Bonewald, Lynda F., Andresen, Jon, Brotto, Marco
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866514/
https://ncbi.nlm.nih.gov/pubmed/27242547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00173
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