Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation

BACKGROUND: Lyn, an import member of Src family kinases (SFKs), is supposed to be implicated in acute myeloid leukemia (AML) pathogenesis and development by participation in AML differentiation, yet the details still remain incompletely understood. The expression status of Lyn and its correlation wi...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cancer Cell Int
المؤلفون الرئيسيون: Iriyama, Noriyoshi, Yuan, Bo, Hatta, Yoshihiro, Takagi, Norio, Takei, Masami
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2016
الموضوعات:
Primary Research
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866426/
https://ncbi.nlm.nih.gov/pubmed/27182202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0314-5
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