Induced Differentiation of Human Myeloid Leukemia Cells into M2 Macrophages by Combined Treatment with Retinoic Acid and 1α,25-Dihydroxyvitamin D(3)

Retinoids and 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) induce differentiation of myeloid leukemia cells into granulocyte and macrophage lineages, respectively. All-trans retinoic acid (ATRA), which is effective in the treatment of acute promyelocytic leukemia, can induce differentiation of othe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Takahashi, Hiromichi, Hatta, Yoshihiro, Iriyama, Noriyoshi, Hasegawa, Yuichiro, Uchida, Hikaru, Nakagawa, Masaru, Makishima, Makoto, Takeuchi, Jin, Takei, Masami
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237509/
https://ncbi.nlm.nih.gov/pubmed/25409436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113722
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