The complete local genotype–phenotype landscape for the alternative splicing of a human exon

The properties of genotype–phenotype landscapes are crucial for understanding evolution but are not characterized for most traits. Here, we present a >95% complete local landscape for a defined molecular function—the alternative splicing of a human exon (FAS/CD95 exon 6, involved in the control o...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Julien, Philippe, Miñana, Belén, Baeza-Centurion, Pablo, Valcárcel, Juan, Lehner, Ben
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866304/
https://ncbi.nlm.nih.gov/pubmed/27161764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11558
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