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Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation

BACKGROUND: Small molecule inhibitor of tyrosine kinase activity, compound SU11274, was reported to have antitumorigenic and antimetastatic effect in melanoma. In this study, we evaluated, whether similar effect could be achieved also in other melanoma cells including highly tumorigenic and hypermet...

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Bibliografiska uppgifter
I publikationen:BMC Cancer
Huvudupphovsmän: Kucerova, Lucia, Demkova, Lucia, Skolekova, Svetlana, Bohovic, Roman, Matuskova, Miroslava
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866285/
https://ncbi.nlm.nih.gov/pubmed/27175734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2341-y
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