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Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation

BACKGROUND: Small molecule inhibitor of tyrosine kinase activity, compound SU11274, was reported to have antitumorigenic and antimetastatic effect in melanoma. In this study, we evaluated, whether similar effect could be achieved also in other melanoma cells including highly tumorigenic and hypermet...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kucerova, Lucia, Demkova, Lucia, Skolekova, Svetlana, Bohovic, Roman, Matuskova, Miroslava
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866285/
https://ncbi.nlm.nih.gov/pubmed/27175734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2341-y
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