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Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation

BACKGROUND: Small molecule inhibitor of tyrosine kinase activity, compound SU11274, was reported to have antitumorigenic and antimetastatic effect in melanoma. In this study, we evaluated, whether similar effect could be achieved also in other melanoma cells including highly tumorigenic and hypermet...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Kucerova, Lucia, Demkova, Lucia, Skolekova, Svetlana, Bohovic, Roman, Matuskova, Miroslava
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866285/
https://ncbi.nlm.nih.gov/pubmed/27175734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2341-y
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