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Generation of stem cell-derived β-cells from patients with type 1 diabetes

We recently reported the scalable in vitro production of functional stem cell-derived β-cells (SC-β cells). Here we extend this approach to generate the first SC-β cells from type 1 diabetic patients (T1D). β-cells are destroyed during T1D disease progression, making it difficult to extensively stud...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Millman, Jeffrey R., Xie, Chunhui, Van Dervort, Alana, Gürtler, Mads, Pagliuca, Felicia W., Melton, Douglas A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866045/
https://ncbi.nlm.nih.gov/pubmed/27163171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11463
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