Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5′-Monophosphate (AMP)-activated Protein Kinase α1

In a microarray study, we found that hepatic miR-291b-3p was significantly increased in leptin-receptor-deficient type 2 mice (db/db), a mouse model of diabetes. The function of miR-291b-3p is unknown. The potential role of miR-291b-3p in regulating hepatic lipid metabolism was explored in this stud...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Meng, Xiangyu, Guo, Jun, Fang, Weiwei, Dou, Lin, Li, Meng, Huang, Xiuqing, Zhou, Shutong, Man, Yong, Tang, Weiqing, Yu, Liqing, Li, Jian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
Onderwerpen:
Lipids
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865911/
https://ncbi.nlm.nih.gov/pubmed/27013659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.713768
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