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Loss of Interleukin-21 Receptor Activation in Hypoxic Endothelial Cells Impairs Perfusion Recovery after Hindlimb Ischemia

OBJECTIVE: Surgical hindlimb ischemia (HLI) in mice has become a valuable preclinical model to study peripheral arterial disease (PAD). We previously identified that the different phenotypical outcomes following HLI across inbred mouse strains is related a region on the short arm of mouse chromosome...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Wang, Tao, Cunningham, Alexis, Dokun, Ayotunde O, Hazarika, Surovi, Houston, Kevin, Chen, Lingdan, Lye, R. John, Spolski, Rosanne, Leonard, Warren J., Annex, Brian H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865891/
https://ncbi.nlm.nih.gov/pubmed/25838422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305476
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