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X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus
Porcine epidemic diarrhea virus (PEDV) is a coronavirus that infects pigs and can have mortality rates approaching 100% in piglets, causing serious economic impact. The 3C-like protease (3CL(pro)) is essential for the coronaviral life cycle and is an appealing target for the development of therapeut...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865815/ https://ncbi.nlm.nih.gov/pubmed/27173881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25961 |
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