Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex

Anticoagulant therapy is used for the prevention and treatment of thromboembolic disorders. Blood coagulation is initiated by the interaction of factor VIIa (FVIIa) with membrane-bound tissue factor (TF) to form the extrinsic tenase complex which activates FX to FXa. Thus, it is an important target...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Barnwal, Bhaskar, Jobichen, Chacko, Girish, Vallerinteavide Mavelli, Foo, Chun Shin, Sivaraman, J., Kini, R. Manjunatha
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865804/
https://ncbi.nlm.nih.gov/pubmed/27173146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25935
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