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Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex
Anticoagulant therapy is used for the prevention and treatment of thromboembolic disorders. Blood coagulation is initiated by the interaction of factor VIIa (FVIIa) with membrane-bound tissue factor (TF) to form the extrinsic tenase complex which activates FX to FXa. Thus, it is an important target...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865804/ https://ncbi.nlm.nih.gov/pubmed/27173146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25935 |
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