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Identification of a α‐helical molten globule intermediate and structural characterization of β‐cardiotoxin, an all β‐sheet protein isolated from the venom of Ophiophagus hannah (king cobra)
β‐Cardiotoxin is a novel member of the snake venom three‐finger toxin (3FTX) family. This is the first exogenous protein to antagonize β‐adrenergic receptors and thereby causing reduction in heart rates (bradycardia) when administered into animals, unlike the conventional cardiotoxins as reported ea...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6459992/ https://ncbi.nlm.nih.gov/pubmed/30891862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3605 |
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