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Effects of Repeated Anesthesia Containing Urethane on Tumor Formation and Health Scores in Male C57BL/6J Mice

Repeated injection of urethane (ethyl carbamate) is carcinogenic in susceptible strains of mice. Most recent cancer studies involving urethane-induced tumor formation use p53(+/–) mice, which lack one copy of the p53 tumor suppressor gene. In contrast, the same protocol elicits at most a single tumo...

Полное описание

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Библиографические подробности
Опубликовано в: :J Am Assoc Lab Anim Sci
Главные авторы: Rex, Tonia S, Boyd, Kelli, Apple, Troy, Bricker-Anthony, Courtney, Vail, Krystal, Wallace, Jeanne
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for Laboratory Animal Science 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865690/
https://ncbi.nlm.nih.gov/pubmed/27177562
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