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Effects of Repeated Anesthesia Containing Urethane on Tumor Formation and Health Scores in Male C57BL/6J Mice
Repeated injection of urethane (ethyl carbamate) is carcinogenic in susceptible strains of mice. Most recent cancer studies involving urethane-induced tumor formation use p53(+/–) mice, which lack one copy of the p53 tumor suppressor gene. In contrast, the same protocol elicits at most a single tumo...
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| Publicado no: | J Am Assoc Lab Anim Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for Laboratory Animal Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865690/ https://ncbi.nlm.nih.gov/pubmed/27177562 |
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