Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer

ZNF322A encoding a classical Cys2His2 zinc finger transcription factor was previously revealed as a potential oncogene in lung cancer patients. However, the oncogenic role of ZNF322A and its underlying mechanism in lung tumorigenesis remain elusive. Here we show ZNF322A protein overexpression in 123...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogene
Prif Awduron: Jen, J, Lin, L-L, Chen, H-T, Liao, S-Y, Lo, F-Y, Tang, Y-A, Su, W-C, Salgia, R, Hsu, C-L, Huang, H-C, Juan, H-F, Wang, Y-C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865475/
https://ncbi.nlm.nih.gov/pubmed/26279304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.296
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