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Sequestration of p53 in the Cytoplasm by Adenovirus Type 12 E1B 55-Kilodalton Oncoprotein Is Required for Inhibition of p53-Mediated Apoptosis

The adenovirus E1B 55-kDa protein is a potent inhibitor of p53-mediated transactivation and apoptosis. The proposed mechanisms include tethering the E1B repression domain to p53-responsive promoters via direct E1B-p53 interaction. Cytoplasmic sequestration of p53 by the 55-kDa protein would impose a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhao, Lisa Y., Liao, Daiqing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC296092/
https://ncbi.nlm.nih.gov/pubmed/14645574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13171-13181.2003
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