Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease

The cytokine TWEAK and its cognate receptor Fn14 are members of the TNF/TNFR superfamily and are upregulated in tissue injury to mediate local tissue responses including inflammation and tissue remodeling. We found that in various models of kidney disease, Fn14 expression (mRNA and protein) is upreg...

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Pubblicato in:PLoS One
Autori principali: Sharif, M. Nusrat, Campanholle, Gabriela, Nagiec, Eva E., Wang, Ju, Syed, Jameel, O’Neil, Shawn P., Zhan, Yutian, Brenneman, Karrie, Homer, Bruce, Neubert, Hendrik, Karim, Riyez, Pullen, Nick, Evans, Steven M., Fleming, Margaret, Chockalingam, Priya, Lin, Lih-Ling
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865213/
https://ncbi.nlm.nih.gov/pubmed/27171494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155368
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