A Mouse Model for Conditional Secretion of Specific Single-Chain Antibodies Provides Genetic Evidence for Regulation of Cortical Plasticity by a Non-cell Autonomous Homeoprotein Transcription Factor

During postnatal life the cerebral cortex passes through critical periods of plasticity allowing its physiological adaptation to the environment. In the visual cortex, critical period onset and closure are influenced by the non-cell autonomous activity of the Otx2 homeoprotein transcription factor,...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Bernard, Clémence, Vincent, Clémentine, Testa, Damien, Bertini, Eva, Ribot, Jérôme, Di Nardo, Ariel A., Volovitch, Michel, Prochiantz, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865174/
https://ncbi.nlm.nih.gov/pubmed/27171438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006035
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