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Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1
Energy homeostasis in eukaryotic cells is a complex and fundamental process that is misregulated in several human diseases. A key component of energy regulation is a process called autophagy that involves the recycling of cellular components. There has been much recent interest in studying the mecha...
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| Veröffentlicht in: | Bioorg Med Chem |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4864979/ https://ncbi.nlm.nih.gov/pubmed/26275681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.07.034 |
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