Whole-cell conversion of l-glutamic acid into gamma-aminobutyric acid by metabolically engineered Escherichia coli

A simple and high efficient way for the synthesis of gamma-aminobutyric acid (GABA) was developed by using engineered Escherichia coli as whole-cell biocatalyst from l-glutamic acid (l-Glu). Codon optimization of Lactococcus lactis GadB showed the best performance on GABA production when middle copy...

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Veröffentlicht in:Springerplus
Hauptverfasser: Ke, Chongrong, Yang, Xinwei, Rao, Huanxin, Zeng, Wenchao, Hu, Meirong, Tao, Yong, Huang, Jianzhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864792/
https://ncbi.nlm.nih.gov/pubmed/27247887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-2217-2
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