Identification of new glutamate decarboxylases from Streptomyces for efficient production of γ-aminobutyric acid in engineered Escherichia coli

BACKGROUND: Gamma (γ)-Aminobutyric acid (GABA) as a bioactive compound is used extensively in functional foods, pharmaceuticals and agro-industry. It can be biosynthesized via decarboxylation of monosodium glutamate (MSG) or L-glutamic acid (L-Glu) by glutamate decarboxylase (GAD; EC4.1.1.15). GADs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Eng
Prif Awduron: Yuan, Haina, Wang, Hongbo, Fidan, Ozkan, Qin, Yong, Xiao, Gongnian, Zhan, Jixun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429771/
https://ncbi.nlm.nih.gov/pubmed/30949236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0154-7
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