Divergent modulation of Rho‐kinase and Ca(2+) influx pathways by Src family kinases and focal adhesion kinase in airway smooth muscle

BACKGROUND AND PURPOSE: The importance of tyrosine kinases in airway smooth muscle (ASM) contraction is not fully understood. The aim of this study was to investigate the role of Src‐family kinases (SrcFK) and focal adhesion kinase (FAK) in GPCR‐mediated ASM contraction and associated signalling eve...

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Библиографические подробности
Опубликовано в: :Br J Pharmacol
Главные авторы: Shaifta, Yasin, Irechukwu, Nneka, Prieto‐Lloret, Jesus, MacKay, Charles E, Marchon, Keisha A, Ward, Jeremy P T, Knock, Greg A
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2015
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864488/
https://ncbi.nlm.nih.gov/pubmed/26294392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13313
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