C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

C4.4A is a modular glycolipid-anchored Ly6/uPAR/α-neurotoxin multidomain protein that exhibits a prominent membrane-associated expression in stratified squamous epithelia. C4.4A is also expressed in various solid cancer lesions, where high expression levels often are correlated to poor prognosis. Ci...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Kriegbaum, Mette Camilla, Jacobsen, Benedikte, Füchtbauer, Annette, Hansen, Gert Helge, Christensen, Ib Jarle, Rundsten, Carsten Friis, Persson, Morten, Engelholm, Lars Henning, Madsen, Andreas Nygaard, Di Meo, Ivano, Lund, Ida Katrine, Holst, Birgitte, Kjaer, Andreas, Lærum, Ole Didrik, Füchtbauer, Ernst-Martin, Ploug, Michael
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864438/
https://ncbi.nlm.nih.gov/pubmed/27169360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25833
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