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A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett’s Esophagus

Biomarkers that drift differentially with age between normal and premalignant tissues, such as Barrett’s esophagus (BE), have the potential to improve the assessment of a patient’s cancer risk by providing quantitative information about how long a patient has lived with the precursor (i.e., dwell ti...

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Curtius, Kit, Wong, Chao-Jen, Hazelton, William D., Kaz, Andrew M., Chak, Amitabh, Willis, Joseph E., Grady, William M., Luebeck, E. Georg
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864310/
https://ncbi.nlm.nih.gov/pubmed/27168458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004919
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