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A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett’s Esophagus

Biomarkers that drift differentially with age between normal and premalignant tissues, such as Barrett’s esophagus (BE), have the potential to improve the assessment of a patient’s cancer risk by providing quantitative information about how long a patient has lived with the precursor (i.e., dwell ti...

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Publicado en:PLoS Comput Biol
Autores principales: Curtius, Kit, Wong, Chao-Jen, Hazelton, William D., Kaz, Andrew M., Chak, Amitabh, Willis, Joseph E., Grady, William M., Luebeck, E. Georg
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864310/
https://ncbi.nlm.nih.gov/pubmed/27168458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004919
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