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A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett’s Esophagus

Biomarkers that drift differentially with age between normal and premalignant tissues, such as Barrett’s esophagus (BE), have the potential to improve the assessment of a patient’s cancer risk by providing quantitative information about how long a patient has lived with the precursor (i.e., dwell ti...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Curtius, Kit, Wong, Chao-Jen, Hazelton, William D., Kaz, Andrew M., Chak, Amitabh, Willis, Joseph E., Grady, William M., Luebeck, E. Georg
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864310/
https://ncbi.nlm.nih.gov/pubmed/27168458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004919
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