A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett’s Esophagus

Biomarkers that drift differentially with age between normal and premalignant tissues, such as Barrett’s esophagus (BE), have the potential to improve the assessment of a patient’s cancer risk by providing quantitative information about how long a patient has lived with the precursor (i.e., dwell ti...

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Detaylı Bibliyografya
Yayımlandı:PLoS Comput Biol
Asıl Yazarlar: Curtius, Kit, Wong, Chao-Jen, Hazelton, William D., Kaz, Andrew M., Chak, Amitabh, Willis, Joseph E., Grady, William M., Luebeck, E. Georg
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864310/
https://ncbi.nlm.nih.gov/pubmed/27168458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004919
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