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A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett’s Esophagus

Biomarkers that drift differentially with age between normal and premalignant tissues, such as Barrett’s esophagus (BE), have the potential to improve the assessment of a patient’s cancer risk by providing quantitative information about how long a patient has lived with the precursor (i.e., dwell ti...

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Publicat a:PLoS Comput Biol
Autors principals: Curtius, Kit, Wong, Chao-Jen, Hazelton, William D., Kaz, Andrew M., Chak, Amitabh, Willis, Joseph E., Grady, William M., Luebeck, E. Georg
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864310/
https://ncbi.nlm.nih.gov/pubmed/27168458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004919
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