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Degenerin channel activation causes caspase‐mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

BACKGROUND: Declines in skeletal muscle structure and function are found in various clinical populations, but the intramuscular proteolytic pathways that govern declines in these individuals remain relatively poorly understood. The nematode Caenorhabditis elegans has been developed into a model for...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: Gaffney, Christopher J., Shephard, Freya, Chu, Jeff, Baillie, David L., Rose, Ann, Constantin‐Teodosiu, Dumitru, Greenhaff, Paul L., Szewczyk, Nathaniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864282/
https://ncbi.nlm.nih.gov/pubmed/27493871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12040
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