Degenerin channel activation causes caspase‐mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

BACKGROUND: Declines in skeletal muscle structure and function are found in various clinical populations, but the intramuscular proteolytic pathways that govern declines in these individuals remain relatively poorly understood. The nematode Caenorhabditis elegans has been developed into a model for...

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Vydáno v:J Cachexia Sarcopenia Muscle
Hlavní autoři: Gaffney, Christopher J., Shephard, Freya, Chu, Jeff, Baillie, David L., Rose, Ann, Constantin‐Teodosiu, Dumitru, Greenhaff, Paul L., Szewczyk, Nathaniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864282/
https://ncbi.nlm.nih.gov/pubmed/27493871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12040
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