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The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function
TORC1 is a master regulator of metabolism in eukaryotes that responds to multiple upstream signaling pathways. The GATOR complex is a newly defined upstream regulator of TORC1 that contains two sub-complexes, GATOR1, which inhibits TORC1 activity in response to amino acid starvation and GATOR2, whic...
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| Pubblicato in: | PLoS Genet |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4864241/ https://ncbi.nlm.nih.gov/pubmed/27166823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006036 |
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