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TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila

In single-cell eukaryotes the pathways that monitor nutrient availability are central to initiating the meiotic program and gametogenesis. In Saccharomyces cerevisiae an essential step in the transition to the meiotic cycle is the down-regulation of the nutrient-sensitive target of rapamycin complex...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wei, Youheng, Reveal, Brad, Reich, John, Laursen, Willem J., Senger, Stefania, Akbar, Tanveer, Iida-Jones, Takako, Cai, Weili, Jarnik, Michal, Lilly, Mary A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284557/
https://ncbi.nlm.nih.gov/pubmed/25512509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419156112
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