Pseudomonas aeruginosa pyocyanin modulates mucin glycosylation with sialyl-Lewis(x) to increase binding to airway epithelial cells

Cystic fibrosis (CF) patients battle life-long pulmonary infections with the respiratory pathogen Pseudomonas aeruginosa (PA). An overabundance of mucus in CF airways provides a favorable niche for PA growth. When compared to that of non-CF individuals, mucus of CF airways is enriched in sialyl-Lewi...

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Dettagli Bibliografici
Pubblicato in:Mucosal Immunol
Autori principali: Jeffries, Jayme L, Jia, Jing, Choi, Woosuk, Choe, Shawn, Miao, Jinfeng, Xu, Ying, Powell, Rebecca, Lin, Jingjun, Kuang, Zhizhou, Gaskins, H Rex, Lau, Gee W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864173/
https://ncbi.nlm.nih.gov/pubmed/26555707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.119
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