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Pyocyanin-induced mucin production is associated with redox modification of FOXA2
BACKGROUND: The redox-active pyocyanin (PCN) is a toxic, secondary metabolite secreted by the respiratory pathogen Pseudomonas aeruginosa (PA). Previously, we have shown that mouse lungs chronically exposed to PCN develop goblet cell hyperplasia and metaplasia (GCHM) and mucus hypersecretion, fibros...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3765780/ https://ncbi.nlm.nih.gov/pubmed/23915402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-82 |
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