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Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes

Human heart failure due to myocardial infarction is a major health concern. The paucity of organs for transplantation limits curative approaches for the diseased and failing adult heart. Human induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) have the potential to provide a long-ter...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Bedada, Fikru B., Wheelwright, Matthew, Metzger, Joseph M.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864165/
https://ncbi.nlm.nih.gov/pubmed/26578113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.11.005
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