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Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes

Human heart failure due to myocardial infarction is a major health concern. The paucity of organs for transplantation limits curative approaches for the diseased and failing adult heart. Human induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) have the potential to provide a long-ter...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Bedada, Fikru B., Wheelwright, Matthew, Metzger, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864165/
https://ncbi.nlm.nih.gov/pubmed/26578113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.11.005
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