Superoxide mediates tight junction complex dissociation in cyclically stretched lung slices

We found that stretching type I rat alveolar epithelial cell (RAEC) monolayers at magnitudes that correspond to high tidal-volume mechanical ventilation results in the production of reactive oxygen species, including nitric oxide and superoxide. Scavenging superoxide with Tiron eliminated the stretc...

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Bibliographic Details
Published in:J Biomech
Main Authors: Song, Min Jae, Davidovich, Nurit, Lawrence, Gladys G., Margulies, Susan S.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864146/
https://ncbi.nlm.nih.gov/pubmed/26592435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2015.10.032
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