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MAPk Activation Modulates Permeability of Isolated Rat Alveolar Epithelial Cell Monolayers Following Cyclic Stretch

We cultured (5 days) rat alveolar epithelial cells to investigate the role of mitogen-activated protein kinase (MAPk) signaling in ventilator induced epithelial barrier dysfunction. Cells were stretched to a magnitude of 12% or 37% change in surface area at a rate of 0.25 Hz with and without pretrea...

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Autori principali: Cohen, Taylor S., Gray Lawrence, Gladys, Khasgiwala, Amit, Margulies, Susan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860996/
https://ncbi.nlm.nih.gov/pubmed/20442784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010385
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