Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPk signalling in skeletal muscle

BACKGROUND: Cancer is considered the second leading cause of death in the world, and for the treatment of this disease, pharmacological intervention strategies are frequently based on chemotherapy. Doxorubicin (DOX) is one of the most widely used chemotherapeutic agents in clinical practice for trea...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: de Lima Junior, Edson Alves, Yamashita, Alex Shimura, Pimentel, Gustavo Duarte, De Sousa, Luís G. O., Santos, Ronaldo Vagner T, Gonçalves, Cinara Ludvig, Streck, Emilio Luiz, de Lira, Fábio Santos, Rosa Neto, Jose Cesar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863825/
https://ncbi.nlm.nih.gov/pubmed/27239415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12104
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