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Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPk signalling in skeletal muscle
BACKGROUND: Cancer is considered the second leading cause of death in the world, and for the treatment of this disease, pharmacological intervention strategies are frequently based on chemotherapy. Doxorubicin (DOX) is one of the most widely used chemotherapeutic agents in clinical practice for trea...
Gespeichert in:
Veröffentlicht in: | J Cachexia Sarcopenia Muscle |
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Hauptverfasser: | , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
John Wiley and Sons Inc.
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863825/ https://ncbi.nlm.nih.gov/pubmed/27239415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12104 |
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