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MicroRNA-129-5p modulates epithelial-to-mesenchymal transition by targeting SIP1 and SOX4 during peritoneal dialysis

Peritoneal dialysis (PD) is the most readily feasible home-dialysis method for renal replacement therapy. However, repeated use of PD can lead to induction of mesothelial/epithelial–mesenchymal transition (MMT/EMT) and fibrosis, eventually leading to ultrafiltration failure and discontinuation of PD...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Lab Invest
Hauptverfasser: Xiao, Li, Zhou, Xun, Liu, Fuyou, Hu, Chun, Zhu, Xuejing, Luo, Ying, Wang, Ming, Xu, Xiaoxuan, Yang, Shikun, Kanwar, Yashpal S, Sun, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863710/
https://ncbi.nlm.nih.gov/pubmed/25961171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.57
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