AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by smurf2 and deubiquitinating enzyme USP4

BACKGROUND: Transforming growth factor-β1 (TGF-β1) plays a key role in mesothelial-to-mesenchymal transition (MMT) during peritoneal dialysis (PD). However, the role of Akt in MMT transformation in PD is not clear. RESULTS: In this study, we observed that the phosphorylated form of protein kinase B...

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Udgivet i:BMC Cell Biol
Main Authors: Xiao, Li, Peng, Xiang, Liu, Fuyou, Tang, Chengyuan, Hu, Chun, Xu, Xiaoxuan, Wang, Ming, Luo, Ying, Yang, Shikun, Song, Panai, Xiao, Ping, Kanwar, Yashpal S, Sun, Lin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369877/
https://ncbi.nlm.nih.gov/pubmed/25885904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0055-7
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