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Somatic Mutations in NEK9 Cause Nevus Comedonicus
Acne vulgaris (AV) affects most adolescents, and of those affected, moderate to severe disease occurs in 20%. Comedones, follicular plugs consisting of desquamated keratinocytes and sebum, are central to its pathogenesis. Despite high heritability in first-degree relatives, AV genetic determinants r...
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| Veröffentlicht in: | Am J Hum Genet |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863661/ https://ncbi.nlm.nih.gov/pubmed/27153399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.03.019 |
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